Propagating Peyote from seeds is a really rewarding experience but require great patience as lophophora williamsii is a really slow growing cactus.
Peyote seeds can remain viable for years if kept dormant in a dry and dark place. You can get seeds from your own cactus plant or here, mature lophophora williamsii flower in response to watering and harvesting will produce a pink fruit containing 6-10 seeds, I sometimes got up to 30 seeds per pod by out crossing them. Peyote flowers should be fertilized with a small paint brush. I practice out crossing to get the most fertile seeds. I transfer some pollen from the flower of one plant to the stigma of another plant.
Seeds of lophophora can germinate all year long in an appropriate environement.
Soil: I got the best result by using ordinary humus, sand, limestone and pumice. Soil must be kept very humid (80-90%) so put more humus than other ingredients - Remove all leaves or wood from the mix, put it inside a small pot and water it. It must be watered for at least 5mn, then just put the seeds and spray water on the peyote seeds to humidify a last time then put in a plastic bag or cover the pot with plastic foil. After a few minutes mist should appear, if it oesnt appear humidity is not enough so just spray again. You are done when mist appears.
Humidity: I wet the soil very much and then I put a plastic over the pot or inside a sandwich plastig bag that can be sealed.
Temperature: 25-30 degrees celcius.
Light: No direct sunlight, they will sprout near a window or they can sprout under an incandecent light or a grolux that you can turn on for 24h . After 2-3 weeks they should all have germinated and they now need 12-14h a day of no direct sunlight. They are still doing fine under a lamp or near a window if you dont have enough sunlight in your area. Note that seeds are living being, some may sprout in a few days, sometimes 1 or 2 but some take more time, can be a few week. Be patient.
When most of the seeds have grown I take away the plastic (folie) after 5-6 weeks, you have to ope the plastic bag a little first, then a little more... or you make holes in the plastic foil if you covered the pot with plastic foila. Then let the soil dry - water - let them dry - water and so on...
After this we can start treating the cacti like adult species and give them less and
less water. Make sure that the soil completely dries out before watering the cacti,
to simulate dry growing conditions.
If the cacti are about one year old (or 1 cm in diameter) you can start thinking
about repotting them. Always keep in mind that a bigger pot is not always better.
Try to get a pot that has about the 3-4 times the diameter and 4-5 times height of
the cactus. Changing pots will give you the opportunity to give the cactus more
nutrients in the new soil. Providing Peyote with a deep pot gives it the
opportunity to grow a healthy tab root.